Prescription-only medicine. Oestrogel is a POM and can only be dispensed against a valid prescription. This listing allows you to pay for dispensing in advance — your original private prescription must reach the pharmacy before your order is dispensed.
About Oestrogel (Estradiol 0.06%) Gel 80g
Oestrogel Pump-Pack is a transdermal hormone replacement therapy containing estradiol 0.06% w/w. It is supplied as an 80g metered-dose pump canister delivering approximately 64 measured doses. Each actuation dispenses 1.25g of gel containing 750 micrograms (0.75mg) of estradiol.
Estradiol is absorbed through the skin into the bloodstream. Oestrogel is prescribed by a doctor or independent prescriber, who will determine whether it is appropriate and at what dose.
Active ingredient
- Estradiol 0.06% w/w
- 750 micrograms estradiol per 1.25g actuation
- Also contains carbomer, trolamine, alcohol and purified water
Dosage
Dosage is determined by the prescriber. The usual starting dose is two actuations daily, delivering 1.5mg of estradiol. The prescriber may adjust this within a range of one to four actuations daily. Always follow the directions on your prescription label and in the Patient Information Leaflet.
People who have a uterus are normally prescribed a progestogen alongside oestrogen therapy to protect the endometrium. Your prescriber will advise on this.
How Oestrogel is applied
- Prime the pump before first use as described in the Patient Information Leaflet.
- Apply to clean, dry, intact skin on the arms, shoulders or thighs.
- Spread thinly over a large area of skin — for example from wrist to shoulder.
- Do not apply to the breasts or the vulval area.
- Allow the gel to dry for at least five minutes before covering the area with clothing.
- Wash your hands after application.
Avoid skin-to-skin contact with the application site until the gel has dried, to reduce the risk of transfer to another person. Do not wash the area or apply other products to it for at least one hour.
Warnings and precautions
The gel is alcohol-based and flammable. Keep away from naked flames and do not smoke until the gel has dried.
Oestrogel is not suitable for everyone. Your prescriber will consider your medical history before prescribing, including any history of breast or other oestrogen-dependent cancer, undiagnosed vaginal bleeding, endometrial hyperplasia, blood clots or clotting disorders, arterial thromboembolic disease, liver disease or porphyria.
Tell your prescriber about all other medicines you take, including liver-enzyme-inducing medicines and any other hormone treatments.
Side effects
Side effects reported with Oestrogel include skin reactions at the application site, headache, breast tenderness, nausea, abdominal pain, bloating, changes in mood and breakthrough bleeding.
Seek medical advice promptly if you notice swelling, redness or pain in a leg, chest pain or breathlessness, yellowing of the skin or eyes, or unexpected vaginal bleeding.
For the full list of side effects, contraindications and precautions, read the Patient Information Leaflet supplied with your medicine.
Storage
Store below 25°C. Keep the pump upright, out of the sight and reach of children. Do not use after the expiry date on the pack.
How to order
- Add this item to your basket and complete checkout to pay for dispensing.
- Send your original private prescription to the pharmacy, either by post to: Unit 4 Crabtree Close, Stoke-on-Trent, ST4 2SW, or electronically to the pharmacy team.
- Your prescription must be dated within the last 28 days.
- Once we have received and clinically checked your prescription, your order is dispensed and dispatched.
More than one item can be dispensed from the same private prescription — add each item to your basket separately.
Do not yet have a prescription?
Live Well Nationwide is developing a private prescribing service for hormone replacement therapy. If you do not currently hold a prescription, contact the pharmacy team on 01782 310001 or by email to ask about availability.
Dispensed by a GPhC-registered pharmacy
Live Well Nationwide is registered with the General Pharmaceutical Council, registration number 9012253. All prescriptions are clinically checked by a registered pharmacist before dispensing.
Do I need a prescription to order Oestrogel?
Yes. Oestrogel is a prescription-only medicine. Paying for this listing reserves and pays for dispensing; it cannot be dispensed until the pharmacy has received a valid prescription.
How do I send my private prescription?
Post the original to Unit 4 Crabtree Close, Stoke-on-Trent, ST4 2SW, or send it electronically to the pharmacy team. Contact us on 01782 310001 if you are unsure which applies to your prescription.
How long is a private prescription valid?
A private prescription for Oestrogel must be dated within the last 28 days. Prescriptions older than this cannot be processed.
How much estradiol does each pump deliver?
Each actuation delivers 1.25g of gel containing 750 micrograms of estradiol. An 80g canister provides approximately 64 measured doses.
Where should the gel be applied?
To clean, dry skin on the arms, shoulders or thighs, spread thinly over a large area. It should not be applied to the breasts or the vulval area.
Do I need to take a progestogen as well?
People who have a uterus are normally prescribed a progestogen alongside oestrogen therapy to protect the womb lining. Your prescriber will decide this and it will be reflected on your prescription.
What should I do if I miss a dose?
Apply it as soon as you remember, unless it is nearly time for the next dose. Do not apply a double dose. Refer to the Patient Information Leaflet or ask your pharmacist.
Can I have several items dispensed from one prescription?
Yes. Add each item to your basket separately and send the prescription covering them all.
How is my order delivered?
Orders are dispatched once the prescription has been received and clinically checked. See our delivery information page for current options.
Can Live Well Nationwide issue the prescription?
A private prescribing service for HRT is in development. Contact the pharmacy team on 01782 310001 to ask about availability.


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